Cisplatin loaded polycaprolactone – zeolite nanocomposite scaffolds for bone cancer treatment
نویسندگان
چکیده
منابع مشابه
Fabrication and Characterization of Polycaprolactone – Zeolite Y Nanocomposite for Bone Tissue Engineering
In recent years, nanoceramics have been used in scaffolds to emulate the nanocomposite with a three-dimensional structure of natural bone tissue. In this regard, polycaprolactone biopolymer is widely used as a scaffold in bone tissue engineering. The goal of this research is to produce porous scaffolds of polycaprolactone - zeolite biocomposite with suitable mechanical, bioactive and biological...
متن کاملBiodegradation and cytotoxicity of ciprofloxacin-loaded hydroxyapatite-polycaprolactone nanocomposite film for sustainable bone implants
INTRODUCTION In recent years there has been a steep increase in the number of orthopedic patients for many reasons. One major reason is osteomyelitis, caused by pyrogenic bacteria, with progressive infection of the bone or bone marrow and surrounding tissues. So antibiotics must be introduced during bone implantation to avoid prolonged infection. AIM The objective of the study reported here w...
متن کاملAligned and random nanofibrous nanocomposite scaffolds for bone tissue engineering
Aligned and random nanocomposite nanofibrous scaffolds were electrospun from polycaprolactone (PCL), poly (vinyl alcohol) (PVA) and hydroxyapatite nanoparticles (nHA). The morphology and mechanical characteristics of the nanofibers were evaluated using scanning electron microscopy and tensile testing, respectively. Scanning electron microscopy revealed fibers with an average diameter of 123 ± 3...
متن کاملGelatin/hydroxyapatite nanocomposite scaffolds for bone repair
The use of bioscaffolds for tissue repair is widely accepted. They can provide structural stability and a 3D system on which cells can grow new tissue. Natural bone is composed of organic (mainly collagen) and mineral biomaterials (predominantly carbonate hydroxyapatite, HA). In recent years, developments in 3D porous-scaffold manufacturing have increased hopes of successful fabrication of stru...
متن کاملEffect of Zeolite and Zeolite/Collagen nanocomposite scaffolds on healing of segmental femur bone defect in rabbits
Objective- The present study was aimed to evaluate repair of a critical segmental defect of rabbit femur using the rabbit’s femoral defects repaired by Zeolite and Zeolite/Collagen scaffolds Design- Experimental Study Animals- Forty-five mature male New Zealand white rabbits Procedures- The animals were randomly divided into three groups of 15 animals each. In the first group...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Science: Advanced Materials and Devices
سال: 2021
ISSN: 2468-2179
DOI: 10.1016/j.jsamd.2021.06.006